Biomarker General Infomation
Biomarker ID
BM003135
Biomarker Name
HLA class I
Disease Dengue
ICD Code ICD-11: 1D20-1D2Z ; ICD-10: A90, R50
Biomarker Type Monitoring
Specific Aim Susceptibility or resistance
Conclusion In ethnic Thais with secondary infections a variety of HLA class I alleles (HLA-A 0203, 0207, A11, B 15, B 44, B 46, B 48, B 51, B 52), DCSIGN promoter polymorphisms and the AB blood group, independently associate with either susceptibility or resistance to dengue fever (DF) and the more severe dengue hemorrhagic fever (DHF).
References
REF 1 HLA and other gene associations with dengue disease severity. Curr Top Microbiol Immunol. 2010;338:99-114. Curr Top Microbiol Immunol. 2010;338:99-114.

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