Biomarker General Infomation
Biomarker ID
BM003211
Biomarker Name
C-X-C chemokine receptor type 5 (CXCR5)
Disease Dengue
ICD Code ICD-11: 1D20-1D2Z ; ICD-10: A90, R50
Biomarker Type Differentiation
Biomarker Measure Increased
Conclusion The CCR5 expression would be promoting an enhanced T cell recruitment into liver, a hypothesis that is corroborated by the CCL5/RANTES increase detected in hepatic tissue from dengue fatal cases.
UniProt ID
References
REF 1 Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever. PLoS One. 2012;7(7):e38527. PLoS One. 2012;7(7):e38527.

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