Biomarker General Infomation |
Biomarker ID |
BM003211 |
Biomarker Name |
C-X-C chemokine receptor type 5 (CXCR5) |
Disease |
Dengue |
ICD Code |
ICD-11: 1D20-1D2Z
; ICD-10: A90, R50
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Increased |
Conclusion |
The CCR5 expression would be promoting an enhanced T cell recruitment into liver, a hypothesis that is corroborated by the CCL5/RANTES increase detected in hepatic tissue from dengue fatal cases. |
UniProt ID |
|
References |
REF 1 |
Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever. PLoS One. 2012;7(7):e38527. PLoS One. 2012;7(7):e38527.
|
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