Biomarker General Infomation |
Biomarker ID |
BM003249 |
Biomarker Name |
Tumor necrosis factor (TNF) |
Disease |
Dengue |
ICD Code |
ICD-11: 1D20-1D2Z
; ICD-10: A90, R50
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Higher |
Conclusion |
Exposure to live dengue virus led to maturation and activation of both the infected and surrounding, uninfected DCs and stimulated production of tumor necrosis factor alpha (TNF-alpha) and alpha interferon (IFN-alpha). |
UniProt ID |
|
References |
REF 1 |
Human dendritic cells are activated by dengue virus infection: enhancement by gamma interferon and implications for disease pathogenesis. J Virol. 2001 Apr;75(8):3501-8. J Virol. 2001 Apr;75(8):3501-8.
|
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