Biomarker General Infomation
Biomarker ID
BM003249
Biomarker Name
Tumor necrosis factor (TNF)
Disease Dengue
ICD Code ICD-11: 1D20-1D2Z ; ICD-10: A90, R50
Biomarker Type Differentiation
Biomarker Measure Higher
Conclusion Exposure to live dengue virus led to maturation and activation of both the infected and surrounding, uninfected DCs and stimulated production of tumor necrosis factor alpha (TNF-alpha) and alpha interferon (IFN-alpha).
UniProt ID
References
REF 1 Human dendritic cells are activated by dengue virus infection: enhancement by gamma interferon and implications for disease pathogenesis. J Virol. 2001 Apr;75(8):3501-8. J Virol. 2001 Apr;75(8):3501-8.

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