| Biomarker General Infomation |
| Biomarker ID |
BM003350 |
| Biomarker Name |
C-X-C chemokine receptor type 4 (CXCR4) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Monitoring |
| Biomarker Measure |
Higher |
| Specific Aim |
Disease progression. |
| Conclusion |
Patients with active visceral leishmaniasis have a higher proportion of circulating CD4+ T-cells expressing CXCR4 than healthy controls, suggesting that Leishmania may facilitate HIV infection of CD4+ lymphocytes. |
| UniProt ID |
|
| References |
| REF 1 |
Increased expression of HIV co-receptor CXCR4 on CD4+ T-cells in patients with active visceral leishmaniasis. Scand J Infect Dis. 2004;36(1):56-8. Scand J Infect Dis. 2004;36(1):56-8.
|
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