| Biomarker General Infomation |
| Biomarker ID |
BM003355 |
| Biomarker Name |
C-X-C chemokine receptor type 3 (CXCR3) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Biomarker Measure |
Decreased |
| Conclusion |
Both CXCR3(+) CD8 T cells and LN CXCR3 ligands decrease as HIV infection progresses, resulting in reduced homing of CTL into LNs and contributing to immune dysfunction. |
| UniProt ID |
|
| References |
| REF 1 |
Decreased CXCR3+ CD8 T cells in advanced human immunodeficiency virus infection suggest that a homing defect contributes to cytotoxic T-lymphocyte ... J Virol. 2007 Aug;81(16):8439-50. J Virol. 2007 Aug;81(16):8439-50.
|
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.
