| Biomarker General Infomation |
| Biomarker ID |
BM003357 |
| Biomarker Name |
Stromal cell-derived factor 1 (CXCL12) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Conclusion |
CXCR4 is a G-protein coupled receptor for CXCL12 that plays an important role in human immunodeficiency virus infection, cancer growth and metastasization, immune cell trafficking and WHIM syndrome. |
| UniProt ID |
|
| References |
| REF 1 |
Ligand-guided optimization of CXCR4 homology models for virtual screening using a multiple chemotype approach. J Comput Aided Mol Des. 2010 Dec;24(12):1023-33. J Comput Aided Mol Des. 2010 Dec;24(12):1023-33.
|
