Biomarker General Infomation |
Biomarker ID |
BM003363 |
Biomarker Name |
C-X-C chemokine receptor type 5 (CXCR5) |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Elevated |
Conclusion |
Elevated levels of CXCL13 could cause impaired or altered trafficking of B cells during HIV infection and could contribute to the previously reported loss of CXCR5, the receptor for CXCL13, from the surface of circulating B cells in HIV infection. |
UniProt ID |
|
References |
REF 1 |
Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection. J Interferon Cytokine Res. 2005 Nov;25(11):702-6. J Interferon Cytokine Res. 2005 Nov;25(11):702-6.
|