Biomarker General Infomation
Biomarker ID
BM003363
Biomarker Name
C-X-C chemokine receptor type 5 (CXCR5)
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Differentiation
Biomarker Measure Elevated
Conclusion Elevated levels of CXCL13 could cause impaired or altered trafficking of B cells during HIV infection and could contribute to the previously reported loss of CXCR5, the receptor for CXCL13, from the surface of circulating B cells in HIV infection.
UniProt ID
References
REF 1 Serum levels of the homeostatic B cell chemokine, CXCL13, are elevated during HIV infection. J Interferon Cytokine Res. 2005 Nov;25(11):702-6. J Interferon Cytokine Res. 2005 Nov;25(11):702-6.

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