Biomarker General Infomation |
Biomarker ID |
BM003364 |
Biomarker Name |
TNF related activation protein (CD40LG) |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Lower |
Conclusion |
HIV infection either selectively depletes those CD4(+) T cells that express CD40L in response to antigen or down-regulates CD40L expression by these cells. |
UniProt ID |
|
References |
REF 1 |
An expanding role for CD40L and other tumor necrosis factor superfamily ligands in HIV infection. J Hematother Stem Cell Res. 2002 Oct;11(5):787-801. J Hematother Stem Cell Res. 2002 Oct;11(5):787-801.
|
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