Biomarker General Infomation |
Biomarker ID |
BM003367 |
Biomarker Name |
Dipeptidyl peptidase 4 (DPP-4) |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Lower |
Conclusion |
HIV infection is characterized by the reduction of the CD4+, CD45RA+, CD26+, and CD28+ lymphocyte subsets and of the in vitro production of IL-2, IL-4, and interferon-gamma; on the contrary, chemokine production is usually increased. |
UniProt ID |
|
References |
REF 1 |
Effects of subcutaneous interleukin-2 therapy on CD4 subsets and in vitro cytokine production in HIV+ subjects. J Clin Invest. 1997 Dec 1;100(11):2737-43. J Clin Invest. 1997 Dec 1;100(11):2737-43.
|