Biomarker General Infomation
Biomarker ID
BM003371
Biomarker Name
Integrin alpha-L
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Differentiation
Biomarker Measure Higher
Conclusion HIV infection of monocytes resulted in twofold elevation of adhesion molecule LFA-1 (both alpha L/CD11a and beta 2/CD18 subunits) and LFA-3 (CD58), with no apparent increase in LFA-2 (CD2) or various beta 1-integrins.
UniProt ID
References
REF 1 HIV-1 infection alters monocyte interactions with human microvascular endothelial cells. J Immunol. 1995 Jan 1;154(1):422-32. J Immunol. 1995 Jan 1;154(1):422-32.

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