| Biomarker General Infomation |
| Biomarker ID |
BM003371 |
| Biomarker Name |
Integrin alpha-L |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Biomarker Measure |
Higher |
| Conclusion |
HIV infection of monocytes resulted in twofold elevation of adhesion molecule LFA-1 (both alpha L/CD11a and beta 2/CD18 subunits) and LFA-3 (CD58), with no apparent increase in LFA-2 (CD2) or various beta 1-integrins. |
| UniProt ID |
|
| References |
| REF 1 |
HIV-1 infection alters monocyte interactions with human microvascular endothelial cells. J Immunol. 1995 Jan 1;154(1):422-32. J Immunol. 1995 Jan 1;154(1):422-32.
|
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