| Biomarker General Infomation |
| Biomarker ID |
BM003386 |
| Biomarker Name |
Extracellular matrix receptor III (CD44) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Conclusion |
CD44 is a marker that can be used to sort neurons from other cell types in brain, suggest the importance of microglia-astrocyte interactions in neurodegenerative mechanisms associated with HIV infection, and indicate a role for insulin-like growth factors in neuroprotection from HIV-induced neurodegeneration. |
| UniProt ID |
|
| References |
| REF 1 |
Reconstitution of human immunodeficiency virus-induced neurodegeneration using isolated populations of human neurons, astrocytes, and microglia and... J Neurovirol. 2006 Dec;12(6):472-91. J Neurovirol. 2006 Dec;12(6):472-91.
|
