| Biomarker General Infomation |
| Biomarker ID |
BM003393 |
| Biomarker Name |
Interleukin-7 (IL7) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Biomarker Measure |
Higher |
| Conclusion |
Elevated levels of interleukin (IL)-7 are present in the blood of HIV-positive patients and it is known that IL-7 receptor (IL-7R)alpha expression decreases on T cells during HIV infection. |
| UniProt ID |
|
| References |
| REF 1 |
Loss of IL-7Ralpha is associated with CD4 T-cell depletion, high interleukin-7 levels and CD28 down-regulation in HIV infected patients. AIDS. 2005 Dec 2;19(18):2077-86. AIDS. 2005 Dec 2;19(18):2077-86.
|
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