Biomarker General Infomation |
Biomarker ID |
BM003393 |
Biomarker Name |
Interleukin-7 (IL7) |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Higher |
Conclusion |
Elevated levels of interleukin (IL)-7 are present in the blood of HIV-positive patients and it is known that IL-7 receptor (IL-7R)alpha expression decreases on T cells during HIV infection. |
UniProt ID |
|
References |
REF 1 |
Loss of IL-7Ralpha is associated with CD4 T-cell depletion, high interleukin-7 levels and CD28 down-regulation in HIV infected patients. AIDS. 2005 Dec 2;19(18):2077-86. AIDS. 2005 Dec 2;19(18):2077-86.
|
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