| Biomarker General Infomation |
| Biomarker ID |
BM003396 |
| Biomarker Name |
T-cell-specific surface glycoprotein CD28 (CD28) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Biomarker Measure |
Lower |
| Conclusion |
CD8(+) T cells become activated (dual expression of DR and CD38) and lose CD28, some acquiring CD57, in relation to rapidity of disease progression in pediatric HIV infection. |
| UniProt ID |
|
| References |
| REF 1 |
Comparison of CD8(+) T-cell subsets in HIV-infected rapid progressor children versus non--rapid progressor children. J Allergy Clin Immunol. 2001 Aug;108(2):258-64. J Allergy Clin Immunol. 2001 Aug;108(2):258-64.
|
