| Biomarker General Infomation |
| Biomarker ID |
BM003397 |
| Biomarker Name |
Thioredoxin (TXN) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Biomarker Measure |
Increased |
| Conclusion |
Increases in plasma Trx levels correlate with decreases in monochlorobimane staining (indicative of lower intracellular glutathione levels in PBMC) and with changes in surface antigen expression (CD62L, CD38 and CD20) that occur in the later stages of HIV infection. |
| UniProt ID |
|
| References |
| REF 1 |
Elevation of plasma thioredoxin levels in HIV-infected individuals. Int Immunol. 1996 Apr;8(4):603-11. Int Immunol. 1996 Apr;8(4):603-11.
|
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