Biomarker General Infomation |
Biomarker ID |
BM003401 |
Biomarker Name |
Leukocyte common antigen (PTPRC) |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Lower |
Conclusion |
The consistent reduction in surface expression of all CD45 isoforms observed in our study may be of relevance to the impaired T cell activation characteristic of HIV infection. |
UniProt ID |
|
References |
REF 1 |
Abnormalities of CD45 isoform expression in HIV infection. Clin Immunol Immunopathol. 1996 Nov;81(2):210-4. Clin Immunol Immunopathol. 1996 Nov;81(2):210-4.
|
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