Biomarker General Infomation
Biomarker ID
BM003413
Biomarker Name
HLA-DR antigens-associated invariant (CD74)
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Differentiation
Biomarker Measure Increased
Conclusion Expression of the CD38, HLA-DR and CD57 markers on CD8 cells was significantly increased in asymptomatic HIV-infected patients when compared with controls, as was the CD8 cell population which did not coexpress Leu-8.
UniProt ID
References
REF 1 The significance of activation markers on CD8 lymphocytes in human immunodeficiency syndrome: staging and prognostic value. Clin Exp Immunol. 1992 Dec;90(3):376-82. Clin Exp Immunol. 1992 Dec;90(3):376-82.

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