Biomarker General Infomation
Biomarker ID
BM003422
Biomarker Name
Interleukin 2 receptor alpha (IL2RA)
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Differentiation
Conclusion Significant changes in IL2R alpha and beta chain expression on circulating T cells occur after HIV infection, but that early activation through IL2 is preserved or enhanced, even in advanced stages.
UniProt ID
References
REF 1 The interleukin-2 receptor subunit expression and function on peripheral blood lymphocytes from HIV-infected and control persons. Clin Immunol Immunopathol. 1994 Apr;71(1):60-8. Clin Immunol Immunopathol. 1994 Apr;71(1):60-8.

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