Biomarker General Infomation |
Biomarker ID |
BM003422 |
Biomarker Name |
Interleukin 2 receptor alpha (IL2RA) |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Conclusion |
Significant changes in IL2R alpha and beta chain expression on circulating T cells occur after HIV infection, but that early activation through IL2 is preserved or enhanced, even in advanced stages. |
UniProt ID |
|
References |
REF 1 |
The interleukin-2 receptor subunit expression and function on peripheral blood lymphocytes from HIV-infected and control persons. Clin Immunol Immunopathol. 1994 Apr;71(1):60-8. Clin Immunol Immunopathol. 1994 Apr;71(1):60-8.
|