Biomarker General Infomation
Biomarker ID
BM003423
Biomarker Name
Interferon-gamma (IFNG)
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Differentiation
Biomarker Measure Decreased
Conclusion The decreased percentage of cells expressing IL-2 and IFN-gamma in conjunction with an increased proportion of IL-4- and IL-10-producing cells among the CD4+ T cells in HIV-1-infected individuals demonstrate a Th1 to Th2 cytokine shift in the course of HIV infection on a single cell level.
UniProt ID
References
REF 1 Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by fl... AIDS. 1997 Jul 15;11(9):1111-8. AIDS. 1997 Jul 15;11(9):1111-8.

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