| Biomarker General Infomation |
| Biomarker ID |
BM003423 |
| Biomarker Name |
Interferon-gamma (IFNG) |
| Disease |
Human immunodeficiency virus infection |
| ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
| Biomarker Type |
Differentiation |
| Biomarker Measure |
Decreased |
| Conclusion |
The decreased percentage of cells expressing IL-2 and IFN-gamma in conjunction with an increased proportion of IL-4- and IL-10-producing cells among the CD4+ T cells in HIV-1-infected individuals demonstrate a Th1 to Th2 cytokine shift in the course of HIV infection on a single cell level. |
| UniProt ID |
|
| References |
| REF 1 |
Demonstration of the Th1 to Th2 cytokine shift during the course of HIV-1 infection using cytoplasmic cytokine detection on single cell level by fl... AIDS. 1997 Jul 15;11(9):1111-8. AIDS. 1997 Jul 15;11(9):1111-8.
|
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