Biomarker General Infomation |
Biomarker ID |
BM003429 |
Biomarker Name |
Eomesodermin homolog |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Differentiation |
Biomarker Measure |
Lower |
Conclusion |
Most cells lost the expression of all cytolytic molecules and Eomesodermin and T-bet in chronic HIV infection. |
UniProt ID |
|
References |
REF 1 |
Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors. Blood. 2012 May 24;119(21):4928-38. Blood. 2012 May 24;119(21):4928-38.
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