Biomarker General Infomation |
Biomarker ID |
BM003430 |
Biomarker Name |
PC4 and SFRS1-interacting protein (PSIP1) |
Disease |
Human immunodeficiency virus infection |
ICD Code |
ICD-11: 1C62
; ICD-10: B17.1, B18.2
|
Biomarker Type |
Monitoring |
Specific Aim |
Resistance |
Conclusion |
Reduced LEDGF/p75 levels may play a role in resistance to HIV-1 infection, while increased tetherin levels could be a marker of advanced HIV disease. |
UniProt ID |
|
References |
REF 1 |
Expression analysis of LEDGF/p75, APOBEC3G, TRIM5alpha, and tetherin in a Senegalese cohort of HIV-1-exposed seronegative individuals. PLoS One. 2012;7(3):e33934. PLoS One. 2012;7(3):e33934.
|