Biomarker General Infomation
Biomarker ID
BM003430
Biomarker Name
PC4 and SFRS1-interacting protein (PSIP1)
Disease Human immunodeficiency virus infection
ICD Code ICD-11: 1C62 ; ICD-10: B17.1, B18.2
Biomarker Type Monitoring
Specific Aim Resistance
Conclusion Reduced LEDGF/p75 levels may play a role in resistance to HIV-1 infection, while increased tetherin levels could be a marker of advanced HIV disease.
UniProt ID
References
REF 1 Expression analysis of LEDGF/p75, APOBEC3G, TRIM5alpha, and tetherin in a Senegalese cohort of HIV-1-exposed seronegative individuals. PLoS One. 2012;7(3):e33934. PLoS One. 2012;7(3):e33934.

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