Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T05849 | Target Info | |||
| Target Name | Gastrin/cholecystokinin type B receptor (CCKBR) | ||||
| Synonyms |
Cholecystokinin-2 receptor; CCKRB; CCK2-R; CCK-BR; CCK-B receptor
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| Target Type | Successful Target | ||||
| Gene Name | CCKBR | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Cholecystokinin receptor type A (CCKAR) | Clinical trial Target | ||||
| UniProt ID | CCKAR_HUMAN | |||||
| Gene Name | CCKAR | |||||
| Synonyms |
CCKAR; CCK-AR; CCK-A receptor
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| Representative Drug(s) | YF-476 | Drug Info | Ki = 28.84 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Optimization of 1,3,4-benzotriazepine-based CCK(2) antagonists to obtain potent, orally active inhibitors of gastrin-mediated gastric acid secretion. J Med Chem. 2007 Jun 28;50(13):3101-12. | ||||
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