Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T29064 Target Info
Target Name Angiogenesis/myeloma cell growth (AMCG)
Target Type Successful Target
Gene Name NO-GeName
UniProt ID
NOUNIPROTAC
Co-Targets of This Target  Top
Co-Target Name Protein cereblon-Zinc finger protein Aiolos complex (CRBN-IKZF3) Co-Target
UniProt ID CRBN_HUMAN-IKZF3_HUMAN
Gene Name CRBN-IKZF3
Representative Drug(s) Pomalidomide Drug Info EC50 = 22 nM [1]
Co-Target Name Protein cereblon-DNA-binding protein Ikaros (CRBN-IKZF1) Co-Target
UniProt ID CRBN_HUMAN-IKZF1_HUMAN
Gene Name CRBN-IKZF1
Representative Drug(s) Pomalidomide Drug Info EC50 = 24 nM [1]
References  Top
REF 1 A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos. J Med Chem. 2018 Jan 25;61(2):535-542.

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