Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T71390 | Target Info | |||
| Target Name | Steroid 5-alpha-reductase 2 (SRD5A2) | ||||
| Synonyms |
Type 2 steroid 5alpha-reductase (5alpha-R); SRD5A2; SR type 2; 5-alpha reductase 2; 5 alpha-SR2
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| Target Type | Successful Target | ||||
| Gene Name | SRD5A2 | ||||
| Biochemical Class | CH-CH donor oxidoreductase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Steroid 5-alpha-reductase 1 (SRD5A1) | Clinical trial Target | ||||
| UniProt ID | S5A1_HUMAN | |||||
| Gene Name | SRD5A1 | |||||
| Synonyms |
SRD5A1; SR type 1; 5-alpha reductase 1
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| Representative Drug(s) | Finasteride | Drug Info | IC50 = 19.8 ug.mL-1 | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | A novel class of inhibitors for steroid 5alpha-reductase: synthesis and evaluation of umbelliferone derivatives. Bioorg Med Chem Lett. 2001 Sep 3;11(17):2361-3. | ||||
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