Co-Target(s) Information

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Target General Information
Co-Targets of This Target
References
Target General Information  Top
Target ID T84886 Target Info
Target Name Solute carrier family 12 member 3 (SLC12A3)
Synonyms
Thiazide-sensitive sodium-chloride cotransporter; Thiazide-sensitive Na-Cl cotransporter; SLC12A3; Na-Cl symporter
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Target Type Successful Target
Gene Name SLC12A3
Biochemical Class Cation-chloride cotransporter
UniProt ID
S12A3_HUMAN
Co-Targets of This Target  Top
Co-Target Name Carbonic anhydrase VII (CA-VII) Patented-recorded Target
UniProt ID CAH7_HUMAN
Gene Name CA7
Synonyms
Carbonic anhydrase 7; Carbonate dehydratase VII
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Representative Drug(s) Metolazone Drug Info Ki = 2.1 nM [1]
References  Top
REF 1 Structure-based screening for the discovery of new carbonic anhydrase VII inhibitors. Eur J Med Chem. 2014 Jan;71:105-11.

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