Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T88185 | Target Info | |||
| Target Name | Nicotinic acid receptor (HCAR2) | ||||
| Synonyms |
Niacin receptor 1; NIACR1; Hydroxycarboxylic acid receptor 2; HM74A; HCA2; GPR109A; G-protein coupled receptor HM74A; G-protein coupled receptor 109A
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| Target Type | Successful Target | ||||
| Gene Name | HCAR2 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Hydroxycarboxylic acid receptor 3 (HCAR3) | Clinical trial Target | ||||
| UniProt ID | HCAR3_HUMAN | |||||
| Gene Name | HCAR3 | |||||
| Synonyms |
Nicotinic acid receptor 2; Niacin receptor 2; NIACR2; HM74B; HCA3; GPR109B; G-protein coupled receptor HM74B; G-protein coupled receptor HM74; G-protein coupled receptor 109B
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| Representative Drug(s) | SCH-900271 | Drug Info | EC50 = 96 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Discovery of SCH 900271, a Potent Nicotinic Acid Receptor Agonist for the Treatment of Dyslipidemia. ACS Med Chem Lett. 2011 Nov 24;3(1):63-8. | ||||
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