Content Navigation
( All
None )
| Target General Information |
Top |
| Target ID |
T88304 |
Target Info
|
| Target Name |
DNA [cytosine-5]-methyltransferase 1 (DNMT1) |
| Synonyms |
MCMT; M.HsaI; Dnmt1; DNMT; DNA methyltransferase HsaI; DNA MTase HsaI; DNA (cytosine5)methyltransferase 1; DNA (cytosine-5)-methyltransferase 1; CXXCtype zinc finger protein 9; CXXC9; CXXC-type zinc finger protein 9; AIM |
| Target Type |
Clinical trial Target |
| Gene Name |
DNMT1 |
| Biochemical Class |
Methyltransferase |
| UniProt ID |
|
| Co-Targets of This Target |
Top |
| Co-Target Name |
Poly [ADP-ribose] polymerase 1 (PARP1) |
Successful Target |
| UniProt ID |
PARP1_HUMAN
|
| Gene Name |
PARP1
|
| Synonyms |
Protein poly-ADP-ribosyltransferase PARP1; Poly[ADP-ribose] synthetase-1; Poly[ADP-ribose] synthase 1; Poly(ADP-ribose)polymerase-1; PPOL; PARP-1; NAD(+)Poly [ADP-ribose] polymerase-1 ADP-ribosyltransferase-1; NAD(+) ADP-ribosyltransferase-1; NAD(+) ADP-ribosyltransferase 1; DNA ADP-ribosyltransferase PARP1; ARTD1; ADPRT 1; ADPRT; ADP-ribosyltransferase diphtheria toxin-like 1 |
| Representative Drug(s) |
CC-486 |
Drug Info
|
Ki = 5.8 nM |
[1] |
| References |
Top |
| REF 1 |
Tricyclic benzimidazoles as potent poly(ADP-ribose) polymerase-1 inhibitors. J Med Chem. 2003 Jan 16;46(2):210-3.
|
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.
