COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02AUY
|
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| Drug Name |
MERS-five-helix bundle
|
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| Synonyms |
MERS-5HB
|
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| Drug Type |
Protein/peptide drug
|
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| Indication | Middle East Respiratory Syndrome (MERS) | Preclinical | [1] | |
| Therapeutic Class |
Antiviral Agents
|
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| Target | Top | |||
|---|---|---|---|---|
| Target(s) | MERS-CoV spike glycoprotein (S) | Target Info | Inhibitor | [1] |
| MERS-5HB effectively inhibits pseudotyped MERS-CoV entry by significantly inhibiting spike (S) glycoprotein-mediated syncytial formation in a dose-dependent manner. | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | Identification of a Novel Inhibitor against Middle East Respiratory Syndrome Coronavirus. Viruses. 2017 Sep 14;9(9). pii: E255. | |||
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