COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02JOA
|
|||
| Drug Name |
Phenylisoserine derivatives SK80
|
|||
| Synonyms |
SK80
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Severe acute respiratory syndrome (SARS) | Preclinical | [1] | |
| Therapeutic Class |
Antiviral Agents
|
|||
| Structure |
 |
Download2D MOL |
||
| Target | Top | |||
|---|---|---|---|---|
| Target(s) | SARS-CoV 3C-like protease (3CLpro) | Target Info | Inhibitor | [1] |
| Phenylisoserine derivatives SK80 is active against SARS CoV 3CL R188I mutant protease with an IC50 value of 43 microM. | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | Synthesis and Evaluation of Phenylisoserine Derivatives for the SARS-CoV 3CL Protease Inhibitor. Bioorg Med Chem Lett. 2017 Jun 15;27(12):2746-2751. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.