COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D04DQT
|
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| Drug Name |
Ribavirin + interferon beta-1a
|
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| Synonyms |
Rebetol + avonex
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| Drug Type |
Combination drug
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| Indication | Middle East Respiratory Syndrome (MERS) | Investigative | [1] | |
| Therapeutic Class |
Antiviral Agents
|
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| Target | Top | |||
|---|---|---|---|---|
| Target(s) | MERS-CoV RNA-directed RNA polymerase (RdRp) | Target Info | Inhibitor | [2] |
| Ribavirin is a nucleoside against MERS-CoV. Its mechanism includes lethal mutagenesis of RNA virus genomes mediated by the MERS-CoV RNA-dependent RNA polymerase. | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | SARS and MERS: recent insights into emerging coronaviruses. Nat Rev Microbiol. 2016 Aug;14(8):523-34. | |||
| 2 | Coronaviruses - drug discovery and therapeutic options. Nat Rev Drug Discov. 2016 May;15(5):327-47. | |||
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