COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09NHD
|
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| Drug Name |
Peptide P21S10
|
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| Synonyms |
P21S10
|
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| Drug Type |
Protein/peptide drug
|
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| Indication | Middle East Respiratory Syndrome (MERS) | Preclinical | [1] | |
| Therapeutic Class |
Antiviral Agents
|
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| Target | Top | |||
|---|---|---|---|---|
| Target(s) | MERS-CoV spike glycoprotein (S) | Target Info | Inhibitor | [1] |
| The resultant stapled peptide P21S10 effectively inhibits infection by MERS-CoV pseudovirus and its spike protein-mediated cell-cell fusion. | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | Discovery of Hydrocarbon-Stapled Short -Helical Peptides as Promising Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Fusion Inhibitors. J Med Chem. 2018 Mar 8;61(5):2018-2026. | |||
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