COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0FP6V
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| Drug Name |
Alpha-Helical lipopeptides IIK
|
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| Synonyms |
IIK
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| Drug Type |
Protein/peptide drug
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| Indication | Middle East Respiratory Syndrome (MERS) | Preclinical | [1] | |
| Therapeutic Class |
Antiviral Agents
|
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| Target | Top | |||
|---|---|---|---|---|
| Target(s) | MERS-CoV spike glycoprotein (S) | Target Info | Inhibitor | [1] |
| Lipopeptides IIK exhibits promising potency against MERS-CoV infection via inhibiting MERS-CoV S protein-mediated cell-cell fusion. | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | De Novo Design of -Helical Lipopeptides Targeting Viral Fusion Proteins: A Promising Strategy for Relatively Broad-Spectrum Antiviral Drug Discovery. J Med Chem. 2018 Oct 11;61(19):8734-8745. | |||
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