COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SU5N
|
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| Drug Name |
PMID28624700-compound-3-31
|
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| Synonyms |
Unsymmetrical aromatic disulfides 3-31
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| Drug Type |
Small molecular drug
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| Indication | Severe acute respiratory syndrome (SARS) | Preclinical | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
 |
Download2D MOL |
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| Target | Top | |||
|---|---|---|---|---|
| Target(s) | SARS-CoV 3C-like protease (3CLpro) | Target Info | Inhibitor | [1] |
| Novel compound 3-31 displays excellent activity (IC50 = 0.516 microM) against main protease of SARS-CoV. | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | Discovery of Unsymmetrical Aromatic Disulfides as Novel Inhibitors of SARS-CoV Main Protease: Chemical Synthesis, Biological Evaluation, Molecular Docking and 3D-QSAR Study Eur J Med Chem. 2017 Sep 8;137:450-461. | |||
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