COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0UT7E
|
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| Drug Name |
Lopinavir + ritonavir + favipiravir
|
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| Synonyms |
Aluviran + norvir + T-705
|
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| Drug Type |
Combination drug
|
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| Indication | Coronavirus Disease 2019 (COVID-19) | Phase 3 | [1] | |
| Therapeutic Class |
Antiviral Agents
|
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| Structure |
 |
Download2D MOL
|
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| Target | Top | |||
|---|---|---|---|---|
| Target(s) | COVID-19 3C-like protease (3CLpro) | Target Info | Inhibitor | [2] |
| Lopinavir/ritonavir blocks viral replication of SARS-CoV-2 via inhibiting the 3C-like protease (3CLpro). | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | ClinicalTrials.gov (NCT04303299) Various Combination of Protease Inhibitors, Oseltamivir, Favipiravir, and Hydroxychloroquine for Treatment of COVID-19 : A Randomized Control Trial | |||
| 2 | Coronavirus puts drug repurposing on the fast track. Nat Biotechnol. 2020 Apr;38(4):379-381. | |||
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