COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0WL2E
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| Drug Name |
PMID30940566-compound-6
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| Synonyms |
PMID30940566-C-6
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| Drug Type |
Small molecular drug
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| Indication | Middle East Respiratory Syndrome (MERS) | Preclinical | [1] | |
| Therapeutic Class |
Antiviral Agents
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| Structure |
 |
Download2D MOL |
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| Target | Top | |||
|---|---|---|---|---|
| Target(s) | MERS-CoV papain-like proteinase (PL-PRO) | Target Info | Inhibitor | [1] |
| Compounds 6 exhibits a promising inhibitory activity against MERS-PLpro protease with IC50 of 20 microM. | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | Identification and Design of Novel Small Molecule Inhibitors Against MERS-CoV Papain-Like Protease via High-Throughput Screening and Molecular Modeling Bioorg Med Chem. 2019 May 15;27(10):1981-1989. | |||
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