COVID-19 Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Z8EV
|
|||
| Drug Name |
Mycophenolic acid
|
|||
| Synonyms |
Acide mycophenolique; Acide mycophenolique [INN-French]; Acido micofenolico; Acido micofenolico [INN-Spanish]; Acidum mycoph; Acidum mycophenolicum; CCRIS 5565; Lilly-68618; Ly 68618; Melbex; Micofenolico acido; Micofenolico acido [Spanish]; Mycophenolate; Mycophenolsaeure; Myfortic; NSC 129185; NSC-129185; UNII-HU9DX48N0T
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Middle East Respiratory Syndrome (MERS) | Investigative | [1] | Coronavirus Disease 2019 (COVID-19) | Investigative | [2] |
| Other Indication | Crohn disease | Approved | [3] | |
| Therapeutic Class |
Antiviral Agents
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C17H20O6
|
|||
| Canonical SMILES |
CC1=C2COC(=O)C2=C(C(=C1OC)CC=C(C)CCC(=O)O)O
|
|||
| InChI |
1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19)/b9-4+
|
|||
| InChIKey |
HPNSFSBZBAHARI-RUDMXATFSA-N
|
|||
| CAS Number |
CAS 24280-93-1
|
|||
| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:168396
|
|||
| Target | Top | |||
|---|---|---|---|---|
| Target(s) | MERS-CoV papain-like proteinase (PL-PRO) | Target Info | Inhibitor | [1] |
| Mycophenolic acid has potential against MERS-CoV through the inhibition of PLpro. | ||||
| References | Top | |||
|---|---|---|---|---|
| 1 | SARS and MERS: recent insights into emerging coronaviruses. Nat Rev Microbiol. 2016 Aug;14(8):523-34. | |||
| 2 | Associations between immune-suppressive and stimulating drugs and novel COVID-19-a systematic review of current evidence. Ecancermedicalscience. 2020 Mar 27;14:1022. | |||
| 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.