Resistance mutation info of drug
| Drug General Information | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Drug ID | D0R3FP | |||||||||||||||
| Drug Name | Tenofovir disoproxil fumarate | |||||||||||||||
| Synonyms | Bis-POC-PMPA; GSK548470; PMPA-oral; Tenofovir DF; Tenozet; Viread | |||||||||||||||
| Drug Type | Small molecular drug | |||||||||||||||
| Therapeutic Class | Antiinfective Agents | |||||||||||||||
| Structure |
|
|||||||||||||||
| Drug Resistance Mutations | ||||||||||||||||
| Target Name | HBV Reverse transcriptase | Target Info | ||||||||||||||
| Uniprot ID | DPOL_HBVB5(347-690) | |||||||||||||||
| Species | Hepatitis B virus genotype B (HBV-B) | |||||||||||||||
| Reference Sequence |
EDWGPCTEHGEHRIRTPRTPARVTGGVFLVDKNPHNTTESRLVVDFSQFSRGNTRVSWPK FAVPNLQSLTNLLSSNLSWLSLDVSAAFYHLPLHPAAMPHLLVGSSGLSRYVARLSSNSR IINNQHRTMQNLHNSCSRNLYVSLMLLYKTYGRKLHLYSHPIILGFRKIPMGVGLSPFLL AQFTSAICSVVRRAFPHCLAFSYMDDVVLGAKSVQHLESLYAAVTNFLLSLGIHLNPHKT KRWGYSLNFMGYVIGSWGTLPQEHIVQKIKMCFRKLPVNRPIDWKVCQRIVGLLGFAAPF TQCGYPALMPLYACIQAKQAFTFSPTYKAFLSKQYLNLYPVARQ [Hepatitis B vi rus genotype B (HBV-B)] |
|||||||||||||||
| Targeted Disease | HBV infection | |||||||||||||||
| Drug Resistance Mutations |
|
|||||||||||||||
| References | ||||||||||||||||
| REF 1 | [Drug-resistant mutations in hepatitis B virus found in chronic HBV carriers using PCR sequencing technology]. Zhonghua Gan Zang Bing Za Zhi. 2016 Jan;24(1):36-9. | |||||||||||||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.