Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00AMQ
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| Former ID |
DAP000681
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| Drug Name |
Ethanol
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| Synonyms |
Aethanol; Aethylalkohol; Alcohol; Alcohols; Algrain; Alkohol; Anhydrol; EOH; EOX; EtOH; Etanol; Etanolo; Ethicap; Ethylalcohol; Ethylol; Hinetoless; Hydroxyethane; Jaysol; Methylcarbinol; QMHAIh; Sekundasprit; Spirit; Spirt; Synasol; Tecsol; Thanol; Absolute alcohol; Absolute ethanol; Aethanol [German]; Alcare Hand Degermer; Alcohol [USP]; Alcohol anhydrous; Alcohol dehydrated; Alcohol etilico; Alcool ethylique; Alcool etilico; Alkohol [German]; Alkoholu etylowego; Anhydrous alcohol; Anhydrous ethanol; Cologne Spirit; Colognespirits; Dehydrated alcohol; Dehydrated ethanol; Denatured alcohol; Denatured ethanol; Desinfektol EL; Distilled spirits; Etanolo [Italian]; Ethanol Absolute; Ethanol Absolute Bp; Ethanol Anhydrous; Ethanol Extra Pure; Ethanol Vapor; Ethanol [JAN]; Ethanol solution; Ethanolum anhydricum; Ethyl alc; Ethyl alcohol; Ethyl alcohol usp; Ethyl hydrate; Ethyl hydroxide; Ethylalcohol [Dutch]; Ethyloxy Group; Etylowy alkohol; Fermentation alcohol; Grain alcohol; HYDROXYETHYL GROUP; Infinity Pure; Jaysol S; Methylated spirit; Molasses alcohol; Oxydimethylene Group; Potato alcohol; Reagent Alcohol; SY Fresh M; Spirits of wine; Spiritus vini; Tecsol C; AHD 2000; Anhydrol PM 4085; CDA 19; E7148_ALDRICH; Esumiru WK 88; Ethanol 200 proof; IMS 99; LTBB002977; SDA 3A; Alcohol (USP); Alcohol, Absolute; Alcohol, Grain; Alcohol, anhydrous; Alcohol, dehydrated; Alcohol, diluted; Alcohol, ethyl; Alcohols, C30; CDA 19-200; Ethanol (9CI); Ethanol, undenatured; Ru-Tuss Expectorant; SDA 40-2; SDM No. 37; ALCOHOL 5% IN D5-W; Alcohols, C1-3; Alcohols, C6-9; (C6-C9)Alkyl alcohol; 1-Hydroxyethane; 100C.NPA
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| Drug Type |
Small molecular drug
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| Indication | Chronic pain [ICD-11: MG30; ICD-10: R52.1, R52.2] | Approved | [1], [2], [3] | |
| Cystitis [ICD-11: GC00] | Approved | [1], [2], [3] | ||
| Therapeutic Class |
Analgesics
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| Structure |
 |
Download2D MOL |
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| Formula |
C2H6O
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| Canonical SMILES |
CCO
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| InChI |
1S/C2H6O/c1-2-3/h3H,2H2,1H3
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| InChIKey |
LFQSCWFLJHTTHZ-UHFFFAOYSA-N
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| CAS Number |
CAS 64-17-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
2694, 3752, 122577, 588484, 601786, 825155, 827842, 841053, 3137603, 7344411, 7847136, 7887325, 7887328, 7889563, 7889631, 7979196, 8145680, 8150751, 10531509, 14709184, 15170309, 17389892, 24439064, 24845303, 24845391, 24845392, 24845393, 24845394, 24845395, 24845396, 24845397, 24845398, 24845399, 24845400, 24845401, 24845402, 24845403, 24845404, 24845405, 24845406, 24845407, 24845408, 24851272, 24854453, 24854455, 24854458, 24854460, 24854502, 24854733, 24856395
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| ChEBI ID |
CHEBI:16236
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| ADReCS Drug ID | BADD_D00061 | |||
| SuperDrug ATC ID |
D08AX08; V03AB16; V03AZ01
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| SuperDrug CAS ID |
cas=000051412
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| Interaction between the Drug and Microbe | Top | |||
|---|---|---|---|---|
| The Metabolism of Drug Affected by Studied Microbe(s) | ||||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Gut microbiota | ||||
| Studied Microbe: Gut microbiota unspecific | [4] | |||
| Description | Ethanol can be metabolized by gut microbiota. | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Antagonist | [5] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2299). | |||
| REF 2 | Preclinical evaluation of riluzole: assessments of ethanol self-administration and ethanol withdrawal symptoms. Alcohol Clin Exp Res. 2009 Aug;33(8):1460-8. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | Ciprofloxacin decreases the rate of ethanol elimination in humans. Gut. 1999 Mar;44(3):347-52. | |||
| REF 5 | DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. | |||
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