Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D00BAJ
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| Former ID |
DIB020134
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| Drug Name |
KH-CB19
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| Synonyms |
KH CB19
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|
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C15H13Cl2N3O2
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| Canonical SMILES |
CCOC(=O)C1=C(C2=C(N1C)C(=C(C=C2)Cl)Cl)C(=CN)C#N
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| InChI |
1S/C15H13Cl2N3O2/c1-3-22-15(21)14-11(8(6-18)7-19)9-4-5-10(16)12(17)13(9)20(14)2/h4-6H,3,18H2,1-2H3/b8-6-
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| InChIKey |
CXJCGSPAPOTTSF-VURMDHGXSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | CDC-like kinase 1 (CLK1) | Target Info | Inhibitor | [2] |
| CDC-like kinase 3 (CLK3) | Target Info | Inhibitor | [2] | |
| Dual-specificity tyrosine-phosphorylation regulated kinase 1A (DYRK1A) | Target Info | Inhibitor | [2] | |
| NetPath Pathway | TCR Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| WikiPathways | mRNA Processing | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Liver X receptors as regulators of macrophage inflammatory and metabolic pathways. Biochim Biophys Acta. 2011 Aug;1812(8):982-94. | |||
| REF 2 | Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing. Chem Biol. 2011 Jan 28;18(1):67-76. | |||
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