Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D00GUM
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| Former ID |
DNC001626
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| Drug Name |
Dilazep
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| Synonyms |
Dilazep; 35898-87-4; Dilazep [INN]; Dilazepum [INN-Latin]; UNII-F8KLC2BD5Z; Dilazepam [INN-Spanish]; F8KLC2BD5Z; CHEMBL126075; Dilazep (INN); Benzoic acid, 3,4,5-trimethoxy-, (tetrahydro-1H-1,4-diazepine-1,4(5H)-diyl)di-3,1-propanediyl ester; NCGC00016747-03; AS 05; DSSTox_RID_80871; DSSTox_CID_25425; DSSTox_GSID_45425; Dilazepum; Dilazepam; Tetrahydro-1H-1,4-diazepine-1,4(5H)-dipropanol 3,4,5-trimethoxybenzoate (diester); 3-{4-[3-(3,4,5-trimethoxybenzoyloxy)propyl]-1,4-diazepan-1-yl}propyl 3,4,5-trimethoxybenzoate
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C31H44N2O10
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| Canonical SMILES |
COC1=CC(=CC(=C1OC)OC)C(=O)OCCCN2CCCN(CC2)CCCOC(=O)C3=CC(=C(C(=C3)OC)OC)OC
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| InChI |
1S/C31H44N2O10/c1-36-24-18-22(19-25(37-2)28(24)40-5)30(34)42-16-8-12-32-10-7-11-33(15-14-32)13-9-17-43-31(35)23-20-26(38-3)29(41-6)27(21-23)39-4/h18-21H,7-17H2,1-6H3
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| InChIKey |
QVZCXCJXTMIDME-UHFFFAOYSA-N
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| CAS Number |
CAS 35898-87-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5021257, 7979090, 8151954, 11112657, 11113524, 11466264, 11467384, 11485968, 14813845, 26751736, 29222219, 47515482, 48110615, 48185145, 48185146, 48259422, 49698400, 49888469, 50575210, 57321593, 85085490, 85788400, 92309007, 96024540, 103358664, 103827128, 103928959, 104171321, 104302450, 109716887, 109716888, 117582298, 124882501, 124882502, 124882503, 125082093, 129083017, 134223538, 134999161, 137241854, 142472737, 144204139, 162092496, 170465831, 176484247, 178101428, 179150376, 184547168, 198939262, 221672745
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| ChEBI ID |
CHEBI:92842
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| SuperDrug ATC ID |
C01DX10
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Solute carrier family 29 member 1 (SLC29A1) | Target Info | Inhibitor | [2] |
| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4717). | |||
| REF 2 | Residues Met89 and Ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, S6-(4-nitrobenzyl)-merc... Mol Pharmacol. 2005 Mar;67(3):837-44. | |||
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