Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02CHG
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| Former ID |
DNC011741
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| Drug Name |
6-Chloro-2-phenyl-chromen-4-one
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| Synonyms |
6-chloroflavone; 10420-73-2; 6-Chloro-2-phenyl-4H-chromen-4-one; 6-Chloro-2-phenyl-chromen-4-one; MLS002701775; CHEMBL293478; 6-chloro-2-phenylchromen-4-one; NSC63999; 4l2f; AC1L6LIW; Maybridge4_000538; AC1Q3RN7; NCIOpen2_003001; Oprea1_047009; SCHEMBL4649891; ZINC58093; DTXSID10289783; MolPort-002-893-915; IFNDLWHUYFSXBK-UHFFFAOYSA-N; HMS1522I10; KS-000017VJ; MRS-1131; NSC621450; BDBM50051364; NSC-63999; 5979AH; AKOS000603599; MCULE-8596095757; MB00919; CCG-233377; NSC-621450; IDI1_031120; NCGC00177472-01; SMR001565369; ZB002315
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C15H9ClO2
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)Cl
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| InChI |
1S/C15H9ClO2/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9H
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| InChIKey |
IFNDLWHUYFSXBK-UHFFFAOYSA-N
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| CAS Number |
CAS 10420-73-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of halogenated/nitrated flavone derivatives and evaluation of their affinity for the central benzodiazepine receptor, Bioorg. Med. Chem. Lett. 7(15):2003-2008 (1997). | |||
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