Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02CKX
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| Former ID |
DAP000762
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| Drug Name |
Carbimazole
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| Synonyms |
Athyromazole; Atirozidina; Basolest; Carbethoxymethimazole; Carbimazol; Carbimazolum; Carbinazole; Carbotiroid; Mertiran; Neomercazole; TYRAZOL; Thyrostat; Carbimazol henning; Carbimazol spofa; CG1; Cg 1; Carbimazol henning (TN); Carbimazole (INN); Carbimazolum [INN-Latin]; Neo-Mercazole; Neo-Thyreostat; Neo-Tireol; Carbimazol [INN-Spanish, French]; Carbimazole [INN:BAN:DCF]; Ethyl 3-methyl-2-sulfanylideneimidazole-1-carboxylate; Ethyl 3-methyl-2-thioimidazoline-1-carboxylate; Ethyl 3-methyl-2-thioxo-2,3-dihydro-1H-imidazole-1-carboxylate; 1-Ethoxycarbonyl-3-methyl-2-thioimidazol; 1-Ethoxycarbonyl-3-methyl-2-thioxo-4-imidazoline; 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo, ethyl ester; 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester; 3-Methyl-2-thioxo-4-imidazoline-1-carboxylic acid ethyl ester; 4-Imidazoline-1-carboxylic acid, 3-methyl-2-thioxo-, ethyl ester
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| Drug Type |
Small molecular drug
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| Indication | Hyperthyroidism [ICD-11: 5A02; ICD-10: E05; ICD-9: 242] | Approved | [1] | |
| Therapeutic Class |
Antithyroid Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C7H10N2O2S
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| Canonical SMILES |
CCOC(=O)N1C=CN(C1=S)C
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| InChI |
1S/C7H10N2O2S/c1-3-11-7(10)9-5-4-8(2)6(9)12/h4-5H,3H2,1-2H3
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| InChIKey |
CFOYWRHIYXMDOT-UHFFFAOYSA-N
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| CAS Number |
CAS 22232-54-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9817, 5179931, 7978859, 8171927, 10321736, 10514044, 11112670, 11373014, 11466467, 11467587, 11484918, 11486133, 11489067, 11491783, 12016059, 15017436, 26612901, 26679438, 26749040, 26749041, 34673253, 46506359, 47499680, 47795165, 47943908, 48019049, 48094653, 48415696, 49698494, 49980624, 50122572, 50122573, 50284853, 51091925, 56313590, 57311057, 85174590, 85788865, 87351869, 87566113, 92124636, 92125424, 92709756, 103649168, 103914223, 104119254, 104309910, 106194732, 117402917, 118307397
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| ChEBI ID |
CHEBI:617099
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| ADReCS Drug ID | BADD_D00360 | |||
| SuperDrug ATC ID |
H03BB01
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| SuperDrug CAS ID |
cas=022232548
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thyroid peroxidase (TPO) | Target Info | Inhibitor | [2] |
| BioCyc | Thyroid hormone biosynthesis | |||
| KEGG Pathway | Tyrosine metabolism | |||
| Metabolic pathways | ||||
| Thyroid hormone synthesis | ||||
| Autoimmune thyroid disease | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| Pathwhiz Pathway | Thyroid hormone synthesis | |||
| Reactome | Thyroxine biosynthesis | |||
| WikiPathways | Hematopoietic Stem Cell Differentiation | |||
| Differentiation Pathway | ||||
| Metabolism of amino acids and derivatives | ||||
| Thyroxine (Thyroid Hormone) Production | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drug information of Carbimazole, 2008. eduDrugs. | |||
| REF 2 | Diagnosis and treatment of thyrotoxicosis in childhood. A European questionnaire study. Eur J Endocrinol. 1994 Nov;131(5):467-73. | |||
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