Drug Information
Drug General Information | Top | |||
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Drug ID |
D05CKR
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Former ID |
DIB010213
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Drug Name |
Nabumetone
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Synonyms |
NNB-001; NNB-004; NNB-005; Nabumetone (oral); Nabumetone (oral), Nobex; 6-MNA (oral), Nobex
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Drug Type |
Small molecular drug
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Indication | Pain [ICD-11: MG30-MG3Z] | Approved | [1], [2] | |
Company |
Nobex Corp
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Structure |
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Download2D MOL |
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Formula |
C15H16O2
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Canonical SMILES |
CC(=O)CCC1=CC2=C(C=C1)C=C(C=C2)OC
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InChI |
1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3
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InChIKey |
BLXXJMDCKKHMKV-UHFFFAOYSA-N
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CAS Number |
CAS 42924-53-8
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PubChem Compound ID | ||||
PubChem Substance ID |
866759, 5089100, 7847491, 7980058, 8139968, 8150030, 8152727, 11112767, 11336025, 11361264, 11364380, 11366942, 11369504, 11373826, 11377666, 11462236, 11466937, 11468057, 11485833, 11486693, 11489785, 11491989, 11495300, 12012677, 15196152, 24897772, 26612514, 26679665, 26748824, 26748825, 29223506, 46507729, 47216826, 47515367, 47662339, 47736536, 47885464, 48035181, 49698816, 49896758, 53786809, 56364587, 56422157, 57322259, 57654458, 80932204, 85087976, 85787391, 92124694, 92125724
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ChEBI ID |
CHEBI:7443
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ADReCS Drug ID | BADD_D01511 |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7245). | |||
REF 2 | ClinicalTrials.gov (NCT01164826) Bioequivalence Study of Nabumetone 750 mg Tablets of Dr. Reddy's Under Fed Conditions. U.S. National Institutes of Health. | |||
REF 3 | Renal effects of nabumetone, a COX-2 antagonist: impairment of function in isolated perfused rat kidneys contrasts with preserved renal function in vivo. Exp Nephrol. 2001;9(6):387-96. |
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