Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07OIX
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| Former ID |
DAP001226
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| Drug Name |
Iodipamide
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| Synonyms |
Adipiodon; Adipiodona; Adipiodone; Adipiodonum; Bilignost; Bilignostum; Biligrafin; Cholografin; Cholospect; IDB; Transbilix; Iodipamic acid; Iodipamide [USAN]; Adipiodona [INN-Spanish]; Adipiodonum [INN-Latin]; Iodipamide (USP); Adipiodone (JAN/INN); N,N''-Adipoyl-bis(3-amino-2,4,6-triiodbenzoesaeure); 3,3'(Adipoyldiimino)bis(2,4,6-triiodobenzoic acid); 3,3'-(Adipoyldiimino)bis(2,4,6-triiodobenzoic acid); 3,3'-Adipoyldiiminobis(2,4,6-triiodobenzoic Acid); 3,3'-[(1,6-DIOXOHEXANE-1,6-DIYL)DIIMINO]BIS(2,4,6-TRIIODOBENZOIC ACID); 3-[5-[(3-CARBOXY-2,4,6-TRIIODO-PHENYL)CARBAMOYL]PENTANOYLAMINO]-2,4,6-TRIIODO-BENZOIC ACID; 3-[[6-(3-carboxy-2,4,6-triiodoanilino)-6-oxohexanoyl]amino]-2,4,6-triiodobenzoic acid
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| Drug Type |
Small molecular drug
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| Indication | Gallbladder disease [ICD-11: DC11.3; ICD-10: K80.2] | Approved | [1], [2], [3] | |
| Therapeutic Class |
Contrast Media
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| Structure |
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Download2D MOL |
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| Formula |
C20H14I6N2O6
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| Canonical SMILES |
C1=C(C(=C(C(=C1I)NC(=O)CCCCC(=O)NC2=C(C=C(C(=C2I)C(=O)O)I)I)I)C(=O)O)I
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| InChI |
1S/C20H14I6N2O6/c21-7-5-9(23)17(15(25)13(7)19(31)32)27-11(29)3-1-2-4-12(30)28-18-10(24)6-8(22)14(16(18)26)20(33)34/h5-6H,1-4H2,(H,27,29)(H,28,30)(H,31,32)(H,33,34)
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| InChIKey |
FFINMCNLQNTKLU-UHFFFAOYSA-N
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| CAS Number |
CAS 606-17-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5243536, 7848837, 7888314, 8027952, 8152362, 11112428, 11466967, 11468087, 11486783, 15040584, 24895909, 29222859, 46507320, 47193872, 47291269, 47291270, 47365354, 48334649, 48416112, 49699217, 49885500, 50100437, 57321966, 57654289, 79570445, 85787388, 87571658, 92125844, 103125333, 103764971, 103914611, 104304379, 117573138, 118307490, 121363515, 124800039, 124882364, 125537198, 134338465, 134359921, 134977667, 137006031, 143432639, 143831592, 144107630, 144207053, 152104311, 160967695, 162880254, 164811140
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| ChEBI ID |
CHEBI:31176
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| ADReCS Drug ID | BADD_D01176 | |||
| SuperDrug ATC ID |
V08AC04
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| SuperDrug CAS ID |
cas=000606177
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Serum albumin (ALB) | Target Info | Binder | [4] |
| Pathway Interaction Database | FOXA2 and FOXA3 transcription factor networks | |||
| Reactome | Platelet degranulation | |||
| Recycling of bile acids and salts | ||||
| HDL-mediated lipid transport | ||||
| Scavenging of heme from plasma | ||||
| WikiPathways | Human Complement System | |||
| Binding and Uptake of Ligands by Scavenger Receptors | ||||
| Lipid digestion, mobilization, and transport | ||||
| Transport of vitamins, nucleosides, and related molecules | ||||
| Bile acid and bile salt metabolism | ||||
| Folate Metabolism | ||||
| Vitamin B12 Metabolism | ||||
| Selenium Micronutrient Network | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7400). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 009321. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | Determining binding sites of drugs on human serum albumin using FIA-QCM. Biosens Bioelectron. 2008 Sep 15;24(1):48-54. | |||
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