Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08IBS
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| Former ID |
DAP000982
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| Drug Name |
Adenine
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| Synonyms |
ADE; ANE; Adenin; Adeninimine; Adenine [JAN]; Pedatisectine B; AD2; Vitamin B 4; Vitamin B4; ALBB-005925; Adenine (8CI); Adenine-ring; B 4, Vitamin; Leuco-4; Leucon (TN); Purine, 6; USAF CB-18; Vitamin-B4; Adenine (JAN/USP); Adenine-8-14C; 1,6-Dihydro-6-Imnopurine; 1,6-Dihydro-6-iminopurine; 1H-Purin-6-amine; 1H-Purin-6-amine (9CI); 1H-Purine, 6-amino; 2'-DEOXY-ADENOSINE-3'-5'-DIPHOSPHATE; 3,6-Dihydro-6-iminopurine; 4, Vitamin B; 6-Amino-1H-purine; 6-Amino-3H-purine; 6-Amino-7H-purine; 6-Amino-9H-purine; 6-Aminopurine; 7H-Purin-6-amine; 9H-Purin-6-amine
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| Drug Type |
Small molecular drug
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| Indication | Malnutrition [ICD-11: 5B50-5B71] | Approved | [1], [2] | |
| Therapeutic Class |
Dietary supplement
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| Structure |
 |
Download2D MOL |
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| Formula |
C5H5N5
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| Canonical SMILES |
C1=NC2=NC=NC(=C2N1)N
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| InChI |
1S/C5H5N5/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H3,6,7,8,9,10)
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| InChIKey |
GFFGJBXGBJISGV-UHFFFAOYSA-N
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| CAS Number |
CAS 73-24-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
2101, 2102, 3447, 540768, 584702, 585680, 589178, 610762, 820745, 822025, 823157, 823652, 823885, 825880, 826914, 827713, 828509, 828511, 830162, 830693, 830719, 830741, 830750, 832226, 836808, 841461, 3135000, 5344002, 5385494, 7847102, 7885703, 7885710, 7885885, 8025117, 8025303, 8144939, 8150497, 10317179, 10322142, 10534154, 11341806, 11361989, 11364000, 11364970, 11366562, 11367532, 11369124, 11370094, 11371752, 11373133
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| ChEBI ID |
CHEBI:16708
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human Deoxyribonucleic acid (hDNA) | Target Info | Binder | [3], [4] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4788). | |||
| REF 2 | Drug information of Adenine, 2008. eduDrugs. | |||
| REF 3 | Escherichia coli DNA adenine methyltransferase: intrasite processivity and substrate-induced dimerization and activation. Biochemistry. 2009 Aug 11;48(31):7399-410. | |||
| REF 4 | Leishmania donovani singly deficient in HGPRT, APRT or XPRT are viable in vitro and within mammalian macrophages. Mol Biochem Parasitol. 2006 Jul;148(1):24-30. | |||
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