Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08VSI
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| Former ID |
DAP001447
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| Drug Name |
Revolade/Promacta
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| Synonyms |
AC1OC7GM
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|
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| Drug Type |
Small molecular drug
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| Indication | Idiopathic thrombocytopenic purpura [ICD-11: 3B64.10; ICD-10: D69.3; ICD-9: 287.31] | Approved | [1] | |
| Chronic liver disease [ICD-11: DB99.0] | Phase 3 | [1] | ||
| Thrombocytopenia [ICD-11: 3B64] | Phase 2 | [1] | ||
| Company |
GSK
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| Structure |
 |
Download2D MOL |
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| Formula |
C22H31Cl
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| Canonical SMILES |
C1CCCC(CC1)CC=CC2=CC(=C(C=C2)C3CCCCC3)Cl
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| InChI |
1S/C22H31Cl/c23-22-17-19(12-8-11-18-9-4-1-2-5-10-18)15-16-21(22)20-13-6-3-7-14-20/h8,12,15-18,20H,1-7,9-11,13-14H2/b12-8-
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| InChIKey |
NDXQJQCGBAIFER-WQLSENKSSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thrombopoietin receptor (MPL) | Target Info | Agonist | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Jak-STAT signaling pathway | ||||
| WikiPathways | Platelet Aggregation (Plug Formation) | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 022291. | |||
| REF 2 | Clinical pipeline report, company report or official report of GlaxoSmithKline (2009). | |||
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