Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09XCX
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| Former ID |
DNC014615
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| Drug Name |
PIRINIXIC ACID
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| Synonyms |
Pirinixic acid; 50892-23-4; WY-14643; [4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid; WY-14,643; WY14643; Wyeth 14,643; Wy 14643; Pirinixic acid [INN]; WY-14643 (Pirinixic Acid); (4-Chloro-6-(2,3-xylidino)-2-pyrimidinylthio)acetic acid; UNII-86C4MRT55A; C14H14ClN3O2S; CCRIS 133; Acidum pirinixicum [INN-Latin]; Acide pirinixique [INN-French]; Acido pirinixico [INN-Spanish]; NSC310038; NSC-310038; NSC 310038; BRN 0759945; ((4-Chloro-6-((2,3-dimethylphenyl)amino)-2-pyrimidinyl)thio)acetic acid; Acetic acid, ((4-chloro-6-(
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| Drug Type |
Small molecular drug
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| Indication | Pulmonary fibrosis [ICD-11: CB03.4; ICD-10: J84.1] | Preclinical | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H14ClN3O2S
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| Canonical SMILES |
CC1=C(C(=CC=C1)NC2=CC(=NC(=N2)SCC(=O)O)Cl)C
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| InChI |
1S/C14H14ClN3O2S/c1-8-4-3-5-10(9(8)2)16-12-6-11(15)17-14(18-12)21-7-13(19)20/h3-6H,7H2,1-2H3,(H,19,20)(H,16,17,18)
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| InChIKey |
SZRPDCCEHVWOJX-UHFFFAOYSA-N
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| CAS Number |
CAS 50892-23-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
454960, 4254149, 5455853, 7980894, 8141096, 8147703, 8153490, 10320072, 11114026, 11120023, 11120511, 11120999, 11121605, 11122085, 11147106, 11362674, 11364765, 11365236, 11367327, 11367798, 11369889, 11370619, 11370620, 11372929, 11373399, 11375489, 11375960, 11378054, 11407059, 11459192, 11460910, 12015627, 14874874, 17396608, 24892928, 26612744, 26652899, 26747165, 26752163, 26752164, 26752165, 26752166, 26759758, 29224731, 47662011, 47959463, 47959464, 48034839, 48413425, 48422051
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| ChEBI ID |
CHEBI:32509
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| References | Top | |||
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| REF 1 | Targeting metabolic dysregulation for fibrosis therapy. Nat Rev Drug Discov. 2020 Jan;19(1):57-75. | |||
| REF 2 | O-arylmandelic acids as highly selective human PPAR alpha/gamma agonists. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3185-90. | |||
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