Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A5JP
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| Former ID |
DIB006130
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| Drug Name |
Iopanoic acid
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| Synonyms |
NSC 41706
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| Drug Type |
Small molecular drug
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| Indication | Vascular disease [ICD-11: BE2Z; ICD-9: 325, 430-459] | Approved | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H12I3NO2
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| Canonical SMILES |
CCC(CC1=C(C(=C(C=C1I)I)N)I)C(=O)O
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| InChI |
1S/C11H12I3NO2/c1-2-5(11(16)17)3-6-7(12)4-8(13)10(15)9(6)14/h4-5H,2-3,15H2,1H3,(H,16,17)
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| InChIKey |
OIRFJRBSRORBCM-UHFFFAOYSA-N
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| CAS Number |
CAS 96-83-3
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:5951
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| Interaction between the Drug and Microbe | Top | |||
|---|---|---|---|---|
| The Abundace of Studied Microbe(s) Regulated by Drug | ||||
| The Order in the Taxonomic Hierarchy of the following Microbe(s): Bacteroidales | ||||
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Studied Microbe: Prevotella copri
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[2] | |||
| Hierarchy | ||||
| Abundance Change | Decrease | |||
| Experiment Method | High-throughput screening | |||
| Description | The abundance of Prevotella copri was decreased by Iopanoic acid (adjusted p-values: 9.02E-04). | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | Extensive impact of non-antibiotic drugs on human gut bacteria. Nature. 2018 Mar 29;555(7698):623-628. | |||
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