Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A7MY
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| Former ID |
DNCL003406
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| Drug Name |
TECFIDERA
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| Synonyms |
DIMETHYL FUMARATE
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| Drug Type |
Small molecular drug
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| Indication | Multiple sclerosis [ICD-11: 8A40; ICD-9: 340] | Approved | [1], [2] | |
| Company |
Biogen Idec
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| Structure |
 |
Download2D MOL |
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| Formula |
C6H8O4
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| Canonical SMILES |
COC(=O)C=CC(=O)OC
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| InChI |
1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+
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| InChIKey |
LDCRTTXIJACKKU-ONEGZZNKSA-N
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| CAS Number |
CAS 624-49-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
86935, 441007, 3139364, 7837333, 8000232, 8704409, 10501789, 10501790, 10530559, 12149507, 15146755, 17397932, 24854591, 29199114, 43759873, 48438655, 49896930, 57407639, 57691297, 77434763, 87569871, 88813806, 91234657, 92729758, 93373832, 99431554, 104669756, 113526872, 121362158, 124759893, 125082069, 126535974, 126651088, 126676165, 134977508, 135158090, 135551773, 135692537, 137117462, 137144088, 143397960, 143855312, 144076332, 152195300, 152258762, 160647607, 160692925, 162038179, 163781403, 164347361
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| ChEBI ID |
CHEBI:76004
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| ADReCS Drug ID | BADD_D00680 | |||
| SuperDrug ATC ID |
N07XX09
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | NFE2-related factor 2 pathway (Nrf2 pathway) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7045). | |||
| REF 2 | Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651. | |||
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