Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0E9BF
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| Former ID |
DIB011740
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| Drug Name |
5-hydroxymethyl-2-furfural
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| Synonyms |
Aes-103; 5-HMF; 5-hydroxymethylfurfural
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| Drug Type |
Small molecular drug
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| Indication | Anemia [ICD-11: 3A00-3A9Z; ICD-9: 280-285] | Phase 2 | [1] | |
| Company |
Aesrx
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| Structure |
 |
Download2D MOL |
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| Formula |
C6H6O3
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| Canonical SMILES |
C1=C(OC(=C1)C=O)CO
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| InChI |
1S/C6H6O3/c7-3-5-1-2-6(4-8)9-5/h1-3,8H,4H2
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| InChIKey |
NOEGNKMFWQHSLB-UHFFFAOYSA-N
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| CAS Number |
67-47-0
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01987908) Evaluation of Different Dose Regimens of Aes-103 Given for 28 Days to Subjects With Stable Sickle Cell Disease. U.S. National Institutes of Health. | |||
| REF 2 | 5-hydroxymethyl-2-furfural modifies intracellular sickle haemoglobin and inhibits sickling of red blood cells. Br J Haematol. 2005 Feb;128(4):552-61. | |||
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