Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0EQ4T
|
|||
| Former ID |
DNC002535
|
|||
| Drug Name |
Guanosine-5'-Triphosphate
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C10H16N5O14P3
|
|||
| Canonical SMILES |
C1=NC2=C(N1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
|
|||
| InChI |
1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
|
|||
| InChIKey |
XKMLYUALXHKNFT-UUOKFMHZSA-N
|
|||
| CAS Number |
CAS 86-01-1
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
3346, 583718, 584137, 585564, 585571, 585586, 637429, 819047, 819066, 821139, 822194, 822537, 823430, 825860, 826359, 827167, 827168, 827169, 827289, 827881, 829136, 830569, 831204, 831803, 831804, 832266, 832716, 833092, 833440, 835915, 839128, 841118, 854938, 6435922, 6435966, 6436440, 6436604, 7888006, 7979471, 8006345, 8006784, 8015743, 8015749, 8026269, 8026273, 8026278, 10317310, 10318490, 10318602, 11532326
|
|||
| ChEBI ID |
CHEBI:15996
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial GTP-binding protein YihA (Bact engB) | Target Info | Inhibitor | [2] |
| GTP cyclohydrolase-I (GCH1) | Target Info | Inhibitor | [2] | |
| Virus RNA-dependent RNA polymerase (Viru RdRP) | Target Info | Inhibitor | [2] | |
| Pathwhiz Pathway | Pterine Biosynthesis | |||
| Reactome | Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1742). | |||
| REF 2 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.